The International Conference on Machine Intelligence and Signal Processing (MISP-2019) will be held at Indian Institute of Technology, Allahabad, India, on September 7-10, 2019. This conference is meant for researchers all over the globe interested in the areas of data mining, artificial intelligence, optimization, machine learning methods/ algorithms, signal processing theory and methods, and applications to human brain disorders like epilepsy, Alzheimer’s, sleep disorders etc. Other applications of machine learning and signal processing techniques are also welcome.