The nervous system is among the most complex and vital biological machinery that mammals have evolved so far. However, it is also one of the most vulnerable to trauma, injury, or autoimmune disorders. For example, neurodegenerative diseases encompass neuronal damage and/or death at accelerated rates and severely impact the central (CNS) as well as the peripheral nervous system (PNS). Since neurons cannot multiply owing to their terminally differentiated state, the sensory, motor, cognition, memory, and behavioral circuitry take a serious hit.